Research Associate 2 MS

Job Details:

Original Posting Date 16-Oct-2009 STARS Requisition number 8478BR Department Pediatrics University Generic Title Bargaining Unit None Job Category Managerial & Professional Type of Employment Full Time Duration Type Fixed If Fixed Duration, Period 1 year from date of hire If Fixed Duration, is continuation possible? Yes (Min/Max)">Salary Grade(Min/Max) (Min/Max)">24 Work Week Standard - 37.5 hrs (M-F, 8:
30-5:
00) Work Location Medical School Campus Worksite Address FMP 425 Position General Purpose The laboratory studies embryonic patterning using the frog model system Xenopus. We are developing new genetic approaches to studying development. In this position, the primary task will be to conduct independent research in optimizing Xenopus genetics. This will include a subset of the following projects:
developing transposon-based transgenic methods to perform insertional mutagenesis, characterize and clone mutants identified in forward genetic screens, optimize mutagenesis methods for forward and reverse screens. Essential Duties 1. Perform and implement an independent research program of a specialized nature:
Generate transgenic X. tropicalis animals for insertional mutagenesis; cross transgenic lines to determine if transposon hops; perform chemical mutagenesis and determine an optimal dose; perform forward genetic screening in X. tropicalis; clone mutants identified in forward genetic screens; identify signaling pathways involved in mutants. 2. Design, develop and modify laboratory protocols independently and after discussion with the PI. Implement a research program to test new scientific hypotheses and experimental methods. 3. Evaluate experimental results including controls; draw conclusions based on this data. Assess the validity of experiments critically. After evaluation of new results, continue or modify the experimental plan independently or with discussion with the Principal Investigator (PI). 4. Survey the scientific literature to identify the latest results/methods that will improve/modify/accelerate the research program. 5. Draft scientific manuscripts or portions of manuscripts; draft written reports to be included in grant proposals or progress reports. 6. Participate in various administrative tasks in the laboratory to insure compliance with research policies at Yale. 7. Teach various laboratory methods to post-doctoral researchers, graduate students and other trainees. Education and Experience 1. Master's Degree in a specific scientific discipline and three years of experience; or an equivalent combination of education and experience. Additional Education and Experience 1. Basic skills in molecular biology. 2. Preferred:
Basic skills and experience with Xenopus as a model system; experience with database design and implementation for recording experimental data. Skills & Abilities 1. Self-motivated and willing to learn new techniques and procedures. 2. Ability to interact well with the laboratory team. 3. Working knowledge of basic computer software such as word processing, email, spreadsheets. 4. Attention to detail, meticulous record keeping of experimental results. 5. Ability to establish priorities for the day to accomplish daily tasks in an efficient manner. Background Check Requirements All external candidates for employment will be subject to pre-employment screening. All offers are contingent on successful completion of a background check. Weekend Hours Required? No Evening Hours Required? No